{"product_id":"big-zone-big-zone-n-o-synergy-90-kapseln-210010","title":"Big Zone N.O Synergy 90 Kapseln","description":"\u003cp\u003e\u003cstrong\u003eN.O. Synergy – the practical pump booster in capsule form\u003c\/strong\u003e\u003cbr\u003e Citrulline, Arginine, Ornithine. These 3 amino acids traditionally constitute the main ingredients of conventional pump boosters. Their mode of action is based on serving as substrates for the synthesis of nitric oxide (N.O.), which is better known by the abbreviation N.O.\u003c\/p\u003e \u003cp\u003eOrnithine and citrulline are converted into arginine in various steps. Arginine is then converted by the enzyme N.O. synthase into the substance that ultimately causes the blood vessels to widen and thus promotes the pump effect.\u003c\/p\u003e \u003cp\u003eHowever, the body already produces N.O. on its own during training to widen the vessels and increase blood flow to the muscles. Whether the body’s own N.O. production or production stimulated externally by citrulline, arginine and co., there are ways to get even more out of this metabolic pathway and take the pump effect to new heights.\u003c\/p\u003e \u003cp\u003eFor this purpose, we developed N.O. Synergy. It can be used as a stand-alone pump booster in capsule form to optimize the body’s own pump effect, or in combination with our Citrulline Malate, Arginine HCL or Shelter to make your muscles practically burst.\u003cbr\u003e  \u003cbr\u003e \u003cstrong\u003eWhat exactly is in it?\u003c\/strong\u003e\u003cbr\u003e \u003cstrong\u003eL-Norvaline\u003c\/strong\u003e\u003cbr\u003e L-Norvaline is a derivative of the essential amino acid L-valine. Research has observed that L-norvaline inhibits the enzyme arginase, which is responsible for breaking down L-arginine in the body.\u003c\/p\u003e \u003cp\u003eThese studies have observed that inhibiting arginine breakdown can allow arginine levels to rise more substantially, thereby contributing to increased N.O. production. This, in turn, could further improve the pump effect.\u003cbr\u003e Pine Bark Extract\u003cbr\u003e However, the arginine level increased by L-norvaline must first be converted into N.O. in order to contribute to increased blood flow. For this reason, we have included a pine bark extract containing a substantial 95 % proanthocyanidins.\u003c\/p\u003e \u003cp\u003eOn the one hand, researchers have observed that proanthocyanidins increase the activity of the enzyme N.O. synthase. This enzyme is responsible for converting arginine into N.O. and could therefore act synergistically with L-norvaline with regard to increased N.O. levels. In addition, studies suggest that the active ingredient may also be able to inhibit the breakdown of N.O. itself, which could allow it to work for longer.\u003cbr\u003e Gymnema Sylvestre Extract\u003cbr\u003e Gymnema Sylvestre is a plant native to Asia, Africa and Australia that has traditionally been used in Ayurvedic medicine. Various studies suggest that the gymnemic acids contained in its leaves may have an effect on the pancreas.\u003c\/p\u003e \u003cp\u003eMore specifically, it is said to protect the cells responsible for insulin secretion from pro-inflammatory cytokines, which can occur when blood sugar levels are elevated, and to have a stimulating effect on insulin secretion when carbohydrates are consumed.\u003c\/p\u003e \u003cp\u003eIncreased insulin secretion could, on the one hand, help carbohydrates be stored in muscle cells more quickly and effectively. On the other hand, studies suggest that insulin could have a stimulating effect on the release of N.O. from the epithelial cells of the blood vessels, which in turn would benefit the pump effect.\u003c\/p\u003e \u003cp\u003eSince many ambitious bodybuilders aim for a high carbohydrate intake particularly before, during and after training to support their training performance, we have used Gymnema Sylvestre with the intention of supporting this approach synergistically and harnessing it for the pump.\u003c\/p\u003e \u003cp\u003eBut don’t worry: if you do not consume carbohydrates before or during training\u003cbr\u003e you will not secrete any additional insulin from Gymnema Sylvestre either.\u003cbr\u003e  \u003cbr\u003e \u003cstrong\u003eBlack Pepper Extract\u003c\/strong\u003e\u003cbr\u003e Black pepper, or more specifically the piperine it contains, is known to promote the bioavailability of various substances. Scientific studies suggest that piperine supports, among other things, the effect of the proanthocyanidins from pine bark extract and could therefore contribute to an improved effect.\u003c\/p\u003e \u003cp\u003e\u003cbr\u003e \u003cstrong\u003eHow should N.O. Synergy be taken?\u003c\/strong\u003e\u003cbr\u003e One serving of N.O. Synergy corresponds to 2 capsules. These should be taken approximately 30 to 45 minutes before training. N.O. Synergy is designed to be effective without any additional intake of Citrulline Malate, Arginine HCL or Shelter. It is therefore ideal as a pump booster in capsule form, which can practically be taken anywhere and requires no further preparation. However, it has also been designed to additionally support the effect of Citrulline Malate, Arginine HCL or Shelter.\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003cbr\u003e N.O. Synergy\u003c\/p\u003e","brand":"Big Zone","offers":[{"title":"Default Title","offer_id":53768254095626,"sku":"210010","price":21.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0892\/6792\/9354\/files\/210010-1.jpg?v=1789802176","url":"https:\/\/mynutrixion.com\/products\/big-zone-big-zone-n-o-synergy-90-kapseln-210010","provider":"My Nutrixion","version":"1.0","type":"link"}